Arkham Asylum is located on the outskirts of Gotham City and is where those of Batman's foes considered to be legally insane are incarcerated (other foes are incarcerated at Blackgate Penitentiary). Although it has had numerous administrators, recent comic books have featured Jeremiah Arkham.

The Elizabeth Arkham Asylum for the Criminally Insane, commonly referred to simply as Arkham Asylum, is a fictional psychiatric hospital in the DC Comics Universe, usually appearing in stories featuring Batman. Many psychopathic criminals from across the DC Universe, mostly from Batman's own rogues gallery (such as the Joker, Poison Ivy, the Riddler, Bane and Two-Face), have been imprisoned within the Asylum.